L6077 - VERATROYLZYGADENINE
VERATROYLZYGADENINE | Product ID | L6077 |
| Name | VERATROYLZYGADENINE |
| Molecular formula | C36H51NO10 |
| Description |
As an analog of Veratridine, it is a Na+ channel activator and a potent neurotoxic. Indeed, it is a depolarizing agent on membranes of nerve terminal, muscle and gland cells. Steroid alkaloid , from plants of the Veratrum genus, Liliaceae |
| Biological activity | It has an effect on cardiac vessel system at the dosage of 1-50 μg/kg (i.v.) |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 80.00 | ||
| 100 mg | 320.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6077 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6077 | Molecular weight | 657.79 g/mol |
| Product name | VERATROYLZYGADENINE | Physical form | |
| CAS No. | 31329-58-5 | Melting point | 259-261 °C |
| RTECS | FL5660000 | Solubility | In chloroform and methanol pyridine Not well in ethanol, chloroform, water, acetone |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 35772 | ||
| Purity | ≥ 96 % (TLC, mass spectrometry) | ||
| Toxicity(LD50) | mice (i.v.): 0.77 (0.66-0.89) mg/kg, (s.c): 9.2 (8.1-10.5) mg/kg | ||
| Chemical Name | 4,9-Epoxycevane-3-beta,4-beta,14,15-alpha,16-beta,20-hexol 3-veratrate | ||
| Storage & Reconstitution Recommandations |
Store at +4°C, in dark place. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L6077 |
| Product name | VERATROYLZYGADENINE |
- Kupchan. "Veratrum alkaloids. XXX. The structure and configuration of zygadenine." J. Amer. Chem. Soc. (1959). 81:1925
- Fink et al., "Veratridine and other depolarizing agents counteract the inhibitory effect of Mg++ ion..."Nannyn-Schmiedeberg’s Arch. Pharmacol. (1990). 342N(1):53-60
- Tarvin et al., "Glucose induced electrical activity in the pancreatic beta-cells: effect of veratridine." Amer. J. Physiol. (1981). 240:127-134
- Honerjager, "A neutrally mediated inotropic effect of veratridine and sevadine on isolated guinea pig papillary muscle." Nannyn Schmiederberg's Arch. Pharmacol. (1980). 314:157-160
Links
| Product code | L6077 |
| Product name | VERATROYLZYGADENINE |
| External Links |
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