(Syn. : TMP=NOH)
TEMPOXIME | Product ID | L9057 |
| Name | TEMPOXIME |
| Molecular formula | C9H18N2O. HCl |
| Description |
a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Hypotensive. Good penetration of biological membranes. Secondary analog of Pempoxime. Antioxidant, radical scavenger. Piperidine derivative, , synthetic. |
| Biological activity | For comparative information see the attached 3 tables. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 x 2mg | 37.00 | ||
| 5 x 2mg | 148.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9057 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9057 | Molecular weight | 206.71 Da. |
| Product name | TEMPOXIME | Physical form | colorless crystal powder. |
| CAS No. | 63467-53-8 | Melting point | ~266 °C (decomp.). |
| RTECS | Solubility | water, ethanol. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 113266 | ||
| Purity | min. 98%. TLC [Silufol UV-254, MeOH:NH3(25%) Rf = 0.69, development with Dragendorff� reagent]; NMR (D2O). |
||
| Toxicity(LD50) | mice (orally): 200-230mg/kg | ||
| Chemical Name | 2,2,6,6-tetramethylpiperidone-4 oxime hydrochloride. | ||
| Storage & Reconstitution Recommandations |
store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 9.66 ml), stable for 1-2 days at 20°C. |
||
| Savety Recommandations | do not swallow or inhale; avoid eye and skin contact. |
||
Bibliographic References
| Product code | L9057 |
| Product name | TEMPOXIME |
- Brehteric et al., Nature (1959). 184:1707-1709
- Lutz et al., J. Org. Chem. (1962) 27(5):1695-1703
- Akhmedkhodzhaeva Kh.S. et al. in Farmakol. alkaloidov ikh proizvod., 1972, Ed. Sultanov M.B., Fan, Tashkent, USSR. 156-162
- Vezen A.E. et al., Dokl. Akad. Nauk Tadzh.SS (1985). CA 104:122584. 28 (6): 350-351
Links
| Product code | L9057 |
| Product name | TEMPOXIME |
| External Links |
PubMed
|
|
Biomedical Citations From PubMed
|
|
|
Toxicology Citations From PubMed
|
|
|
PubChem CID
|
|
