(Syn. : TMP)
TEMPIDINE | Product ID | L9059 |
| Name | TEMPIDINE |
| Molecular formula | C9H19N.HCl |
| Description |
a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Hypotensive. Good penetration of biological membranes. Secondary analog of Pempidine and Temechine. Antioxidant, radical scavenger. Piperidine derivative, , synthetic. |
| Biological activity | For comparative information see the attached 4 tables. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 x 5mg | 44.00 | ||
| 5 x 5mg | 176.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9059 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9059 | Molecular weight | 177.71 Da. |
| Product name | TEMPIDINE | Physical form | colorless crystal powder. |
| CAS No. | 768-66-1 (base), 935-22-8 (HCl). | Melting point | 299-301 °C. |
| RTECS | Solubility | water, ethanol. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 120465 | ||
| Purity | min. 98%. TLC (Silufol UV-254, MeOH:NH3(25%) Rf 0.26, development with Dragendorff� reagent); NMR (D2O). |
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| Toxicity(LD50) | mice (orally): 220 mg/kg [1]. mice (i.v.): 32.5 mg/kg. mice (i.p.): 94mg/kg. |
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| Chemical Name | 2,2,6,6-tetramethylpiperidine hydrochloride. | ||
| Storage & Reconstitution Recommandations |
store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 11.24 ml), stable for 1-2 days at 20°C. |
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| Savety Recommandations | do not swallow or inhale; avoid eye and skin contact. |
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Bibliographic References
| Product code | L9059 |
| Product name | TEMPIDINE |
- Brehteric et al., Nature (1959). 184:1707-1709
- Lee et al., Nature (1958). 181:1717
- Spinks et al., Nature (1959). 181:1397
- Tichonenko V.M., Farm.Toxikol. (1962). 25(6): 689-705
- Filipport E. et al., Arch. Int. Pharmacod. Ther. (1962). 135(3-4):273-280
- Hall H.K., Jr., JACS (1957). 79(20): 5444-5447
Links
| Product code | L9059 |
| Product name | TEMPIDINE |
| External Links |
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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