It is a blocker of Apamin-sensitive Ca²⁺-activated K⁺ channels.

Scyllatoxin (Leiurotoxin I) completely inhibits Apamin binding to rat brain synaptosomal membranes (Ki = 75 pM). Like Apamin, Scyllatoxin blocks the epinephrine-induced relaxation of guinea pig teniae coli (ED₅₀ = 6.5 nM). A series of analogs that allow the use of different labeling techniques have also been prepared: the [Tyr²] Scyllatoxin analog, allowing labelling by iodination, is available.

Stable in freeze-dried state.
In solution, keep at -20 °C.

For research use only — not intended for food, diagnostic or therapeutic use