L9039 - QUIRESTON
QUIRESTON | Product ID | L9039 |
| Name | QUIRESTON |
| Molecular formula | C8H14INO |
| Description |
a potent inhibitor of high-affinity choline uptake (HAChU) in synaptosomes; acetylcholine synthesis inhibitor; weak penetration of biological membranes. Quinicludine derivative, , synthetic. |
| Biological activity | cell impermeable inhibitor of high-affinity choline uptake (HAChU). For comparative information see the attached table. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 530.00 | ||
| 100 mg | 2 120.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9039 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9039 | Molecular weight | 267.11 Da. |
| Product name | QUIRESTON | Physical form | slightly yellowish crystal powder. |
| CAS No. | 6659-51-4 | Melting point | 275-277 °C. |
| RTECS | Solubility | water, ethanol and DMSO. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 201716 | ||
| Purity | min. 99.5%. (NMR (D2O)). | ||
| Toxicity(LD50) | mice (orally) >500 mg/kg | ||
| Chemical Name | 3-quinuclidon methoiodide; 1-methyl-3-oxoquinuclidium iodide. | ||
| Storage & Reconstitution Recommandations |
store in a dark place in a dessicator; solutions are stable for 1-2 days at room temperature. Solution for use: 10-3M (2 mg in 7.49 ml). |
||
| Savety Recommandations | |||
Bibliographic References
| Product code | L9039 |
| Product name | QUIRESTON |
- Dahlbom R. et al., "Cell Mol. Basis Cholinergic Funct.", Dowdall M. J. and Hawthorne J. N. Eds., Horwood, Chichester U.K., (1987) 347-354
- Sterling et al., "Inhibition of high-affinity choline uptake and acetylcholine synthesis by quinuclidinyl and hemicholinium derivatives", J. Neurochem.(1986). 46(14):1170-1175
- Doukas P.H. et al., ibid, 355-1175
- Baltzod F. et al., Biochem. Pharm. (1980). 29(18):2413-2416
- Tamaru M. et al., Brain Res (1988). 473(2):205-226
- Dowdall M.J. et al., in Cholinergic mechanisms and Psycopharmacology, Ed. D.J.Jenden, Plenum Press, N-Y, (1978). 359
Links
| Product code | L9039 |
| Product name | QUIRESTON |
| External Links |
PubMed
|
|
Biomedical Citations From PubMed
|
|
|
Toxicology Citations From PubMed
|
|
|
PubChem CID
|
|
