Q Bu
Product ID L9061 
Name Q Bu 
Molecular formula C11H22BrN
Description

Rigid bicyclic analog of TMA and TEA. Molecular probe for calibration of the size of ion channels or receptors sites. Nicotinic AChR blocker. Acetylcholinesterase inhibitor. Lipid layers modifier.


Quaternary quinuclidine derivative, , synthetic.
Biological activity

Nicotinic AChR : less active than Tetraethylammonium (TEA) and Tetramethylammonium (TMA).

Acetylcholinesterase: TMA Ki = 187mM; TEA, 104 mM; QBu, 5.1 mM
Lipid bilayer modifier.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 690.00

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100 mg 2 760.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L9061 : unit price : free of charge
 Chemical and Physical Properties
Product code L9061  Molecular weight 248.20 Da.
Product name Q Bu  Physical form colorless crystal powder.
CAS No. 3837-34-1 Melting point 233-235 °C.
RTECS Solubility water, ethanol.
UNIPROT Optical Activity
PubChem SID    
PubChem CID    
Purity min. 98%. (NMR (D2O))    
Toxicity(LD50) mice (orally): 450mg/kg    
Chemical Name 1-n-butylquinuclidinium bromide, N-n-butylquinuclidinium bromide.    
Storage & Reconstitution
Recommandations

store at room temperature in a dark place, in a dessicator (extremely hygroscopic). Solution for use: dissolve in water: 10-3M (2 mg in 8.06 ml), stable for 1-2 days at 20°C.


 
Savety Recommandations

do not swallow or inhale; avoid eye and skin contact.

 
 Bibliographic References
Product code L9061 
Product name Q Bu 

- Kellet et al., J. Pharm. Sci. (1966). 55(3):414-417
- Barlow, Molec. Pharm. (1971). 7(4):357
 Links
Product code L9061 
Product name Q Bu 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
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