L8408-1MG - PLA2 Apis mellifera
(Syn. : Allergen Api m I)
(Syn. : Allergen Api m I)
PLA2 Apis mellifera | Product ID | L8408-1MG |
| Name | PLA2 Apis mellifera |
| Molecular formula | C664H1012N186O202S13 |
| Description |
It is the main antigen of bee venom, causing hydrolysis of erythrocytes and mast cells membrane phospholipids, and acting in synergy with Melittin. 134-amino acid protein with 5 disulfite bonds , from Apis mellifera bee venom. |
| Biological activity | It has an effect at more than 850 units/mg protein at pH 8.9 at 25 °C., using egg yolk phosphatidylcholine. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 Unité(s) | 98.00 | ||
| 5 Unité(s) | 392.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8408-1MG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8408-1MG | Molecular weight | ~ 18,500 Da |
| Product name | PLA2 Apis mellifera | Physical form | |
| CAS No. | Melting point | ||
| RTECS | SZ6114950 | Solubility | In water |
| UNIPROT | P00630 | Optical Activity | |
| PubChem SID | |||
| PubChem CID | |||
| Purity | > 96 % (HPLC) | ||
| Toxicity(LD50) | IPR-MUS LD50: 5 mg/kg SCU-MUS LD50: 1200 õg/kg IVN-MUS LD50: 7500 õg/kg |
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| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Stable in dried state; Store at 4 °C. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L8408-1MG |
| Product name | PLA2 Apis mellifera |
- Hollander et al., "Characterization of the oligosaccharide structures on bee venom phospholipase A2." Carbohydrate Research (1993). 247:291-297
- Kubelka et al., "Primary structures of the N-linked carbohydrate chains from honeybee venom phospolipase A2." European Journal of Biochemistry (1993). 213(3):1193-1204
- Prenner et al., "The antigenicity of the carbohydrate moiety of an insect glycoprotein, honey-bee (Apis mellifera) venom phospholipase A2: the role of alpha 1,3-fucosylation of the asparagine-bound N-acetylglucosamine." Biochemical Jl (London 1984) (1992)
- Slotta et al., "Enzymatic and toxic activity of phospholipase A." in A. De Vries and E. Kochva, Eds., Toxins of Animal and Plant Origin, Vol. I, Gordon and Breach, New-York (1971), 401-418.
Links
| Product code | L8408-1MG |
| Product name | PLA2 Apis mellifera |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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 UNIPROT |
