(Syn. : Pirilene, PMP)
PEMPIDINE Tartrate | Product ID | L9043 |
| Name | PEMPIDINE Tartrate |
| Molecular formula | C10H21N .C4H6O6 |
| Description |
a neuronal nicotinic AChR antagonist. Potent ganglioblocker. Antihypertensive. Good penetration of biological membranes. Monocyclic analog of TEMECHINE. Piperidine derivative, , synthetic. |
| Biological activity | For comparative information see the attached tables. Cell permeant central nicotinic acetylcholine receptor blocker without action on skeleton muscle innervation. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 86.00 | ||
| 100 mg | 344.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9043 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9043 | Molecular weight | 305.37 Da. |
| Product name | PEMPIDINE Tartrate | Physical form | colorless crystal powder |
| CAS No. | 79-55-0 (base), 546-48-5 (tartrate), 6152-93-8 (tosilate). | Melting point | 150-151°C |
| RTECS | Solubility | water, ethanol. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 120729 | ||
| Purity | min. 98%. TLC (Silufol UV-254, MeOH:NH3(25%) Rf 0.78, development with Dragendorff� reagent); NMR (D2O). |
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| Toxicity(LD50) | mice (orally): 275 mg/kg | ||
| Chemical Name | 1,2,2,6,6-pentamethylpiperidine d-tartrate. | ||
| Storage & Reconstitution Recommandations |
store at room temperature. Solution for use: dissolve in water: 10-3M (2 mg in 6.56 ml), stable for 1-2 days at 20°C. |
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| Savety Recommandations | Do not swallow or inhale; avoid eye and skin contact. |
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Bibliographic References
| Product code | L9043 |
| Product name | PEMPIDINE Tartrate |
- Lee J.E. et al., Nature (1958) 181:1717
- Romano C. et al, Psychopharmacologie (1981) 74(4):310-315
- Mader et al., "Voltage dependent blocade of a crustacean muscle", J. Exp. Biol. (1980). 88:147-159
- Lingle, J. Physio. (1983) (London). 339:419-437
- Tichonenko V.M., Farm.Toxikol.(Kiev) (1980). (13):109-125 (1978); [p.42-44 Engl.]., CA 93: 762
- Rapier C. et al., Neuropharm. (1990). 54(3):937-945
- Spinks et al., Nature (1958). 181:1397
- Corne et al., Brit.J.Pharm. (1958). 13(5):501-520
- Spinks et al., Brit.J.Pharm. (1958). 13(4):501-520
Links
| Product code | L9043 |
| Product name | PEMPIDINE Tartrate |
| External Links |
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