CONOTOXIN MVII C (Omega-)
Product ID L8504-100UG 
Name CONOTOXIN MVII C (Omega-) 
Molecular formula C106H178N40O32S7
Description

It is a blocker of omega-conotoxin GVIA-insensitive Ca2+ channels, including P-type Ca2+-channels in cerebellar Purkinge cells.


A 26-amino acid peptide with 3 disulfide bridges , synthetic, originally from Conus magus molluscan venom
Biological activity

ω-CgTx-MVIIC inhibits presynaptic Ca2+ channels, including the Ca2+ channels responsible for Ca2+ uptake by rat brain synaptosomes, the P-type Ca2+ channels in cerebellar Purkinje cells, and a significant fraction of Omega-CgTx-GVIA-resistant currents in hippocampal CA1 neurons.
ω-CgTx-MVIIC also presents an inhibition of Omega-CgTx-GVIA-resistant depolarization-induced neurotransmitter release in cerebellar neurons of rats

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
1 Unité(s) 110.00

add to cart add to cart

5 Unité(s) 440.00

add to cart add to cart

For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L8504-100UG : unit price : free of charge
 Chemical and Physical Properties
Product code L8504-100UG  Molecular weight 2749.25 Da
Product name CONOTOXIN MVII C (Omega-)  Physical form white powder
CAS No. 147794-23-8 Melting point
RTECS Solubility In water, saline.
UNIPROT P37300 Optical Activity
PubChem SID    
PubChem CID 56841670    
Purity > 99%. Reverse phase HPLC, capillary electrophoresis    
Toxicity(LD50)    
Chemical Name    
Storage & Reconstitution
Recommandations

Stable in freeze-dried state.
In solution, keep at -20°C.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L8504-100UG 
Product name CONOTOXIN MVII C (Omega-) 

- Hillyard et al., "A new Conus peptide ligand for mammalian presynaptic Ca2+ channels." Neuron (1992). 9:69-77
 Links
Product code L8504-100UG 
Product name CONOTOXIN MVII C (Omega-) 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
UNIPROT
click to zoom

LOGIN
Welcome, click here to   Login !




Adress:
ZA Les Auréats, 845 Avenue Pierre Brossolette
26800 PORTES lès VALENCE - FRANCE

Phone:
+33 475 419 191

Email:
latoxan[@]latoxan.com

Web link:
www.latoxan.com