It is an inhibitor of carbachol-stimulated phosphoinositide turnover. It enhances the ability of Forskolin to augment cAMP levels in brain slices.
It is also an antitussive.

Noscapine is an antitussive agent, acting on a Central Nervous System site. However, unlike Codeine and other narcotics, Noscapine lacks addictive, analgesic, respiratory depressant, and sedative properties.
High affinity [³H]Noscapine binding sites are brain specific and ion insensitive. Although Noscapine (up to 1 mM) does not affect directly basal Phosphoinositide turnover or cAMP levels, it inhibits Carbachol-stimulated Phosphoinositide turnover (EC₅₀ = 10 μM), and augments the stimulation by Forskolin of cAMP levels (EC₅₀ = 50 μM).

Store at +4 °C, in dark place.

For research use only — not intended for food, diagnostic or therapeutic use