NITRARINE Di-HCl
Product ID L6068 
Name NITRARINE Di-HCl 
Molecular formula C20H25N3.2HCl
Description

It is a hypotensive, a spasmolytic, a coronary dilator and a sedative in experimental arrhythmias.


Alkaloid , from plants of the Zygophyllaceae family
Biological activity

In experimental arrhythmias in the cat, caused by calcium chloride, Aconitine and electric cardiac stimulation, Nitrarine dihydrochloride presents a hypotensive, spasmolytic, coronary dilating and sedative action. Its antiarrhythmic properties are due to its stabilizating effects on the membrane and its coronary dilating action. Nitrarine dihydrochloride is 3-4 times as potent as Novocainamide and Quinidine, and the duration of its effect is 2-5 times longer than that of these products.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
50 mg 80.00

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250 mg 320.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6068 : unit price : free of charge
 Chemical and Physical Properties
Product code L6068  Molecular weight 380.35 g/mol
Product name NITRARINE Di-HCl  Physical form
CAS No. 20069-05-0 Melting point 265-266 °C
RTECS Solubility Well in water, methanol and ethanol
UNIPROT Optical Activity
PubChem SID    
PubChem CID 6419917    
Purity > 97 %    
Toxicity(LD50) IVN-MUS LD50: 117 mg/kg (1 % solution), (hypodermally): 520 mg/kg (2 % solution)    
Chemical Name 4,14,20-triazahexacyclo[13.6.2.02,14.03,11.05,10.016,21]tricosa-3(11),5,7,9-tetraene;dihydrochloride    
Storage & Reconstitution
Recommandations

Store at +4 °C, in dark place.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6068 
Product name NITRARINE Di-HCl 

- Nasirov et al. Chem. Nat. Comp. (1976). 3:334-345
- Aminov et al. Chem. Pharm. J. (1991) (Russian). 3:56-58
 Links
Product code L6068 
Product name NITRARINE Di-HCl 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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