L9069 - NICARDIPINE HCl
(Syn. : YC-93 HCl, Nicodel, Perdipine)
(Syn. : YC-93 HCl, Nicodel, Perdipine)
NICARDIPINE HCl | Product ID | L9069 |
| Name | NICARDIPINE HCl |
| Molecular formula | C26H29N3O6.HCl |
| Description |
a L-type Ca2+ channels blocker; antihypertensive. Dihydropyridine derivative, , synthetic. |
| Biological activity | Inhibits L-type Ca2+ channels in chick sensory neurons [4]. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 230.00 | ||
| 100 mg | 920.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L9069 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L9069 | Molecular weight | 515.99 Da. |
| Product name | NICARDIPINE HCl | Physical form | light yellow solid. |
| CAS No. | 54527-84-3 | Melting point | 168-170 °C. |
| RTECS | Solubility | in dilute aqueous alkaline solution and chloroform-methanol (1:1); not in water. | |
| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 41114 | ||
| Purity | min. 99%. (TLC) | ||
| Toxicity(LD50) | rat (orally): 187 mg/kg; rat (i.v.): 15.5 mg/kg; mice (orally): 322 mg/kg; mice (i.v.): 19.9 mg/kg. rat (i.p.): 155 mg/kg; rat (s.c.): 683 mg/kg; mice (i.p.): 123 mg/kg; mice (s.c.): 540 mg/kg. |
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| Chemical Name | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2- [methyl-(phenylmethyl)amino]ethyl ester hydrochloride. | ||
| Storage & Reconstitution Recommandations |
stable when kept dry; store at room temperature in a dark place. |
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| Savety Recommandations | do not inhale nor swallow, prevent contact with skin. |
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Bibliographic References
| Product code | L9069 |
| Product name | NICARDIPINE HCl |
- Triggle et al., TiPS (1989). 10:507-511
- Sato et al., "Mechanism of Mesaconitine-induced contractile response in guinea-pig ileum." J. Pharm. Pharmacol. (1980). 7:249
- Chang et al., Can. J. Physiol. Pharmacol. (1989). 67:1493
- Aosaki et al., "Characterization of two kinds of high-voltage-activated Ca-channel currents in chick sensory neurons." Pflügers Arch. (1989). 414:150-156
Links
| Product code | L9069 |
| Product name | NICARDIPINE HCl |
| External Links |
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