L6030 - HERNANDEZINE
HERNANDEZINE | Product ID | L6030 |
| Name | HERNANDEZINE |
| Molecular formula | C39H44N2O7 |
| Description |
It is probably a calcium antagonist, a platelet aggregation inhibitor an anti-inflammatory and an analgesic. Bisbenzylisoquinoline alkaloid , from plants of the Thalictrum genus, Ranunculaceae. |
| Biological activity | It inhibits rat platelet aggregation induced by collagen, ADP, A23187 and arachidonic acid and inhibits A23187-induced concentration increase of cytosolic free calcium in human platelet. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 204.80 | ||
| 100 mg | 819.20 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6030 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6030 | Molecular weight | 652.78 g/mol |
| Product name | HERNANDEZINE | Physical form | Powder |
| CAS No. | 6681-13-6 | Melting point | 156-157 °C |
| RTECS | Solubility | In chloroform Not well in ethanol, methanol |
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| UNIPROT | Optical Activity | [alpha]D +216° (c=1, chloroform) | |
| PubChem SID | |||
| PubChem CID | 72343 | ||
| Purity | > 95% (HPLC) | ||
| Toxicity(LD50) | SCU-MUS LD50: 282 mg/kg SCU-RAT LD50: 175 mg/kg |
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| Chemical Name | (1beta)-5,6,6',7,12-pentamethoxy-2,2'-dimethylberbaman | ||
| Storage & Reconstitution Recommandations |
Store at +4°C, in dark place. |
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| Savety Recommandations | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use |
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Bibliographic References
| Product code | L6030 |
| Product name | HERNANDEZINE |
- Shu-Hua Chen et al., "Calcium antagonists from traditional Chinese herbs." Drug News and Perspectives (1990). 3(7):425-428
- M. Shamma et al., Chem. Comm., (1966). 7
- Sadritdinov, "Alkaloid inflammatory effects of Hernandezine and some of its action mechanisms." Alkaloid and heart glycoside pharmacology, Tashkent, (1971) (Russian). 117-120
Links
| Product code | L6030 |
| Product name | HERNANDEZINE |
| External Links |
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