GLYROPHAMA Dihydrate
Product ID L6090 
Name GLYROPHAMA Dihydrate 
Molecular formula C34H40O16.H2O
Description

It is an antiatherosclerotic and angioprotective. It reduces platelet aggregation and it reduces dysfunction of the hypophyseal/gonadic system.


Rotenoid glycoside , from plants of the Leguminosae Family
Biological activity

On experimental atherosclerosis in rabbit, Glyrophama dihydrate presents the following effects:
- It reduces the area of the aorta damage by ~ 35 % or more;
- It lowers (~ 2 times) the serumal global cholesterol, free cholesterol, cholesterol esters, and triglycerides level;
- It enhances the HDL (a-cholesterol);
- It prevents the aorta and vessels permeability due to hypocholesterolemia, acid acetic, formol, or external proteins;
- It reduces the platelet aggregation, the hypercoagulation syndrom;
- It reduces the hypophyseal/gonadic system dysfunction.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
50 mg 82.50

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250 mg 330.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6090 : unit price : free of charge
 Chemical and Physical Properties
Product code L6090  Molecular weight 722.7 g/mol
Product name GLYROPHAMA Dihydrate  Physical form Powder
CAS No. 4207-90-3 Melting point 158-161 °C
RTECS BT6779100 Solubility In pyridine, DMSO
Not well in ethanol 95 % and acetone
Not in chloroform and water
UNIPROT Optical Activity
PubChem SID    
PubChem CID 122792    
Purity >97 %    
Toxicity(LD50) ORL-MUS LD50: 255 mg/kg    
Chemical Name (2R)-8,9-Dimethoxy-2alpha-[1-[(6-O-alphaL-arabinopyranosyl-b-D-glucopyranosyl)oxymethyl]ethenyl]-1,2,12,12aalpha-tetrahydro[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aalphaH)-one    
Storage & Reconstitution
Recommandations

Stable in dry state.
Store at +4°C, in dark place.
For in vitro experiments, the active concentration in DMSO is 10-6-10-9 M.


 
Savety Recommandations

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use

 
 Bibliographic References
Product code L6090 
Product name GLYROPHAMA Dihydrate 

- Acree et al., J. Org. Chem. (1973). 8:572
- Kurmukov et al., J. Mol. Cell. Cardiol. (1989). 21(suppl. 4):S15
- Aizikov et al., J. Mol. Cell. Cardiol. (1993). 25 (suppl.)
 Links
Product code L6090 
Product name GLYROPHAMA Dihydrate 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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