L8111-1MG - ERABUTOXIN b
(Syn. : ETXB)
(Syn. : ETXB)
ERABUTOXIN b | Product ID | L8111-1MG |
| Name | ERABUTOXIN b |
| Molecular formula | C286H451N87O94S8 |
| Description |
It is an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. It differs from L8110 Eraburoxin a with an histidine at residue 26. 62-amino acid peptide with 4 disulfide bridges , from Laticauda semifasciata snake venom. |
| Biological activity | Erabutoxin b is a reversible nicotinic receptor antagonist which binds to the acetylcholine receptors of Torpedo marmorata electric organs: Kd = 4 x 10-11 M. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 Unité(s) | 245.00 | ||
| 5 Unité(s) | 980.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8111-1MG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8111-1MG | Molecular weight | 6868.69 Da |
| Product name | ERABUTOXIN b | Physical form | |
| CAS No. | 9083-23-2 | Melting point | |
| RTECS | KD8012000 | Solubility | In water and saline |
| UNIPROT | Q90VW1 | Optical Activity | |
| PubChem SID | |||
| PubChem CID | 16132266 | ||
| Purity | |||
| Toxicity(LD50) | IMS-RAT LD50: 70 õg/kg IMS-MUS LD50: 150 õg/kg IVN-MUS LDLo: 2.63 õg/kg |
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| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Stable in freeze-dried state. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L8111-1MG |
| Product name | ERABUTOXIN b |
- Tamiya et al., Biochem. J. (1966). 99:624
- Ishikawa et al., "Current view of the structure-function relationship of postsynaptic neurotoxins from snake venoms." Toxicon (1977). 15:477
- Chiappinelli et al., Brain Res. (1981). 211:107
- Endo et al. "Current view on the structure-function relationship of postsynaptic neurotoxins from snake venoms." Pharmac. Ther. (1987). 34:403-451
Links
| Product code | L8111-1MG |
| Product name | ERABUTOXIN b |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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PubChem CID
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