It is a nicotinic cholinoreceptor antagonist at the neuromuscular junction and a curare-like ganglioblocker.

It is a curare-form competitive anti-depolarizing muscle relaxant. It is used for muscle relaxation and controlled breathing under narcosis during surgical operations. It can be used for tracheal intubation.

It is less potent than d-Tubocurarin. In humans, (i.v.) 1.5-2 mg/kg causes muscle relaxation without breathing suppression, 4-5 mg/kg in 4-5 min complete myorelaxation and apnoe for 20-30 min.

Decurarization is gradual: after restoration of spontaneous breathing abdominal and limbs muscles relaxation for some time. To prolong the action of Diplacine the repeated dose must be 1.5-2 times lower.

The effect is antagonized by Proserine.
It doesn't lead to histamine liberation, nor laringo- or bronchoconstriction. High doses may induce 15-20 mmHg blood pressure increase.

Stable in dry state up to 100 °C, solutions are stable for 1-2 days.<br>Solution for use: 10-³ M (2 mg in 3.64 ml).

highly toxic! Do not swallow nor inhale; avoid eye and skin contact.<br>For research use only — not intended for food, diagnostic or therapeutic use