DELCORINE
Product ID L6052 
Name DELCORINE 
Molecular formula C26H41NO7
Description

It is an antiarrhythmic and hypotensive agent, a ganglioblocker and presents weak affinity at brain Alpha-Bungarotoxin-sensitive nAChR.


Alkaloid , from plants of the Ranunculaceae family.
Biological activity

The antiarrhythmic effects of Delcorine: ED50 on various models of experimental arrhythmias (i.v.) ranges from 10 to 20 mg/kg. At these concentrations, the product blocks, during a short period, the neuronal conductivity in sympathetic ganglia and causes hypotension.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 104.00

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100 mg 416.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6052 : unit price : free of charge
 Chemical and Physical Properties
Product code L6052  Molecular weight 479 g/mol
Product name DELCORINE  Physical form
CAS No. 52358-55-1 Melting point 202-203 °C
RTECS Solubility In chloroform
Not well in ethanol and methanol
UNIPROT Optical Activity
PubChem SID    
PubChem CID 6713960    
Purity 97% (TLC, mass spectrometry)    
Toxicity(LD50) IVN-MUS LD50: 116 mg/kg
IPR-MUS LD50: 590 mg/kg
   
Chemical Name (1S,4S,5R,6S,12R,13R,16S,19S,21S)-14-ethyl-4,6,19-trimethoxy-16-(methoxymethyl)-9,11-dioxa-14-azaheptacyclo[10.7.2.12,5.01,13.03,8.08,12.016,20]docosan-21-ol    
Storage & Reconstitution
Recommandations

Store at +4°C, in dark place.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6052 
Product name DELCORINE 

- Narzullaev et al., Chem. Nat. Comp. (1973). 4:497
- Salimov et al., Chem. Nat. Comp. (1985). 1:95
 Links
Product code L6052 
Product name DELCORINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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