HYDRASTINE (D-beta-) - Latoxan Valence France

HYDRASTINE (D-beta-)

Product ID	L6031
Name	HYDRASTINE (D-beta-)
Molecular formula	C₂₁H₂₁NO₆
Description	It is a potent GABA_A competitive antagonist, twice as potent as Bicuculline. Phthalide isoquinoline alkaloid , from the plant Corydalis pseudoadunca, Fumariaceae.
Biological activity	D-beta Hydrastine acts as a competitive antagonist of GABA. GABA-activated currents, in rat isolated neurons, are strongly and reversibly blocked by an external application of D-beta Hydrastine and its effect is similar but twice as potent as that of D-Bicuculline.

Packaging and Prices

Packaging	Price (€)	Buy Now
50 mg	75.00	add to cart
250 mg	375.00	add to cart
For quotation of big quantities, please Contact us

Product Technical Documents

	Safety Data Sheet Available on request, please Contact us Ref. SDS_L6031 : unit price : free of charge

Chemical and Physical Properties

Product code	L6031	Molecular weight	383.39 g/mol
Product name	HYDRASTINE (D-beta-)	Physical form
CAS No.	118-08-1	Melting point	125-132 °C
RTECS	MU6030000	Solubility	In chloroform Slightly in methanol and ethanol Practically not in water
UNIPROT		Optical Activity
PubChem SID
PubChem CID	197835
Purity	98 %
Toxicity(LD50)	IVN-MUS LD50: 0.102 mg/kg SCU-MUS LD50: 0.96 mg/kg
Chemical Name	(3S)-6,7-dimethoxy-3-[(5R)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one
Storage & Reconstitution Recommandations	Store at +4°C, in dark place.
Savety Recommandations	For research use only — not intended for food, diagnostic or therapeutic use

Bibliographic References

Product code	L6031
Product name	HYDRASTINE (D-beta-)

- Chernevskaja et al., "Inhibitions of the GABA-induced currents of rat neurons by the alkaloid isocoryne from the plant Corydalis pseudoadunca." Toxicon (1990). 28(6):727-730

Links

Product code	L6031
Product name	HYDRASTINE (D-beta-)
External Links	PubMed
	Biomedical Citations From PubMed
	Toxicology Citations From PubMed

	PubChem CID

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