L8223 - Bj-xtrlT (recombinant)
(Syn. : Beta-insect excitatory toxin Bj-xtrIT)
(Syn. : Beta-insect excitatory toxin Bj-xtrIT)
Bj-xtrlT (recombinant) | Product ID | L8223 |
| Name | Bj-xtrlT (recombinant) |
| Molecular formula | |
| Description |
It is an excitatory anti-insect selective scorpion beta-toxin. Polypeptide of 76-amino acids cross-linked by 4 disulfide bridges. Recombinant toxin produced in Eschirichia coli initialy from Buthotus judaicus scorpion venom. |
| Biological activity | It is toxic exclusively to insects with an effective dose 50% in blowfly larvae (ED50) of 14 ng/100 mg body weight. The equilibrium dissociation constant, Kd, has been determined in binding assays to cockroach neuronal membranes = 0.15 nM (ref. 3). |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 x 50ug | 118.00 | ||
| 1 Unité(s) | 128.00 | ||
| 5 x 50ug | 472.00 | ||
| 5 Unité(s) | 512.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8223 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8223 | Molecular weight | 8,575 Da |
| Product name | Bj-xtrlT (recombinant) | Physical form | |
| CAS No. | Melting point | ||
| RTECS | Solubility | In water and aqueous solutions | |
| UNIPROT | P56637 | Optical Activity | No optical Activity |
| PubChem SID | |||
| PubChem CID | |||
| Purity | > 98 % | ||
| Toxicity(LD50) | No mammal toxicity | ||
| Chemical Name | |||
| Storage & Reconstitution Recommandations |
Store at 4°C |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L8223 |
| Product name | Bj-xtrlT (recombinant) |
- Froy, O., Zilberberg, N., Gordon, D., Turkov, M., Gilles, N., Stankiewicz, M., Pelhate, M., Loret, E., Oren, D., Shaanan, B. and Gurevitz, M. (1999) The putative bioactive surface of insect-selective scorpion excitatory neurotoxins. J.Biol.Chem. 274, 5769
- Oren, D. A., Froy, O., Amit, E., Kleinberger-Doron, N., Gurevitz, M. and Shaanan, B. (1998) An excitatory scorpion toxin with a distinctive feature: an additional a-helix at the C-terminus and its implications for interaction with insect sodium channels.
- Cohen, L., Karbat, I., Gilles, N., Froy, O., Angelovici, R., Gordon, D., Gurevitz, M.(2004) Dissect. of the functional surface of an anti-insect excit. toxin illuminates a putative 'hot spot' common to all scorpion beta-toxins affecting Na channels, J.Bi
Links
| Product code | L8223 |
| Product name | Bj-xtrlT (recombinant) |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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 UNIPROT |
