L8116-1MG - BUNGAROTOXIN (beta-)
(Syn. : beta-BuTX, Basic phospholipase A2 beta-bungarotoxin)
(Syn. : beta-BuTX, Basic phospholipase A2 beta-bungarotoxin)
BUNGAROTOXIN (beta-) | Product ID | L8116-1MG |
| Name | BUNGAROTOXIN (beta-) |
| Molecular formula | ò1 and ò2 subunits |
| Description |
It is a Phospholipase A2 composed of β1 subunit (120-amino acid) and β2 subunit (61-amino acid) linked by disulfide bridges , from Bungarus multicinctus snake venom |
| Biological activity | As phospholipas A2, it is a selective inhibitor of the acetylcholine release at the neuromuscular junction. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 Unité(s) | 152.00 | ||
| 5 Unité(s) | 608.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8116-1MG : unit price : free of charge |
Chemical and Physical Properties
| Product code | L8116-1MG | Molecular weight | 20,500 Da (13,500 Da + 7,000 Da) |
| Product name | BUNGAROTOXIN (beta-) | Physical form | White solid |
| CAS No. | 65862-89-7 & 82446-04-6 | Melting point | |
| RTECS | EI6202000 & EI6202000 | Solubility | Well in water, saline and buffer (add saline or buffer after complete solubilization in water). |
| UNIPROT | P00617;P00987 | Optical Activity | No optical Activity |
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| Purity | > 97% (PAGE analysis, FPLC) | ||
| Toxicity(LD50) | IVN-MUS LD50: 10 üg/kg IPR-MUS LD50: 19 üg/kg SCU-MUS LD50: 40 üg/kg IMU-MUS LD50: 89 üg/kg |
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| Storage & Reconstitution Recommandations |
Store at + 4°C |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L8116-1MG |
| Product name | BUNGAROTOXIN (beta-) |
- Dreyer et al., "The actions of presynaptic snake toxins on membrane currents of mouse motor nerve terminals." J. Physiol. (1987). 386:445
- Chu Chen-Chung et al.,"The non-phospholipase A2 subunit of b-bungarotoxin plays an important role in the phospholipase A2-independent neurotoxic effect: characterization of three isotoxins with a common phospholipase A2 subunit." Biochem. J. 303(1):171(94
- Rowan et al., "Potassium channel blocking actions of b-bungarotoxin and related toxins on mouse and frog motor nerve terminals." Br. J. Pharmacol. (1988). 94:839
- Abe et al., "Isolation and characterization of presynaptically acting neurotoxins from the venom of Bungarus snakes." Eur. J. Biochem. (1977). 80:1
- Strong, "Potassium channel toxins." Pharmac. Ther. (1990). 46:137
Links
| Product code | L8116-1MG |
| Product name | BUNGAROTOXIN (beta-) |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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