ASKENDOSIDE D
Product ID L6015 
Name ASKENDOSIDE D 
Molecular formula C45H74O17
Description

It is a cardiac glycoside used in treatment of cardiac failure.


Glycoside , from Astragalus taschkendicus of the Leguminosae family.
Biological activity

Askendoside D presents a high selectivity for the cardiac Na+/K+-ATPase, with practically no activity on brain or kidney Na+/K+-ATPases, as compared with other cardiac glycosides (unpublished).
It is also an interferon inducer with antiviral and anticancer properties.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
10 mg 112.00

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50 mg 448.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6015 : unit price : free of charge
 Chemical and Physical Properties
Product code L6015  Molecular weight 887.1 g/mol
Product name ASKENDOSIDE D  Physical form Powder
CAS No. 86408-17-5 Melting point 235-236 °C
RTECS Solubility In DMSO, pyridine
Not well in water and alcohol.
UNIPROT Optical Activity [alpha]D20 -9.1° ± 2° (c = 1.1 in pyridine)
PubChem SID 103476520    
PubChem CID 21630099    
Purity 99.99 % (TLC, mass spectrometry, NMR)    
Toxicity(LD50) IPR-RAT LD0: no mortality at 1 000 mg/kg    
Chemical Name (2S,3R,4S,5R)-2-[[(1S,3R,6S,8R,9S,11S,12S,14S,15R,16R)-6-[(2S,3R,4S,5R)-4,5-dihydroxy-3-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-14-hydroxy-15-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyloxolan-2-yl]-7,7,12,16-tetramethyl-9-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]oxy]oxane-3,4,5-triol    
Storage & Reconstitution
Recommandations

Store at +4°C, in dark place.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6015 
Product name ASKENDOSIDE D 

- Isaev M.I. et al., Chem.Nat.Comp. (1989). 2:131
- Isaev M.I. et al., Chem.Nat.Comp. (1983). 2:170
 Links
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