ACECLIDINE
Product ID L9065 
Name ACECLIDINE 
Molecular formula C9H15NO2 .C7H6O3
Description

It is a selective M-AChR agonist with a rigid bicyclic analog of ACh. 


Quinuclidine derivative , synthetic
Biological activity

5-10 μg/kg i.v. in cats cause hypotension. 1.5x10-6 M in cats cause myosis. 3x10-8 M in isolated rabbit intestine cause contractions.

It has a good penetration of biological membranes.

It has a more potent than NMQ-OAc.

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 424.00

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100 mg 1 696.00

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For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L9065 : unit price : free of charge
 Chemical and Physical Properties
Product code L9065  Molecular weight 307.34 g/mol
Product name ACECLIDINE  Physical form colorless crystal powder
CAS No. 6821-59-6 Melting point 137-141°C
RTECS VO6380000 Solubility In water, ethanol
UNIPROT Optical Activity No optical activity
PubChem SID    
PubChem CID 23260    
Purity min. 98% (TLC (MeOH-NH3 25% [10:1], Rf=0.40, Sulifol); NMR (D2O))    
Toxicity(LD50) mice (p.o.) > 650mg/kg; (s.c.): 112.5 mg/kg    
Chemical Name DL-3-acetoxyquinuclidine salicylate    
Storage & Reconstitution
Recommandations

Store at room temperature.

Solution for use: dissolve in water: 10-3M (2 mg in 6.51 ml), stable for 1-2 days at 20°C.


 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L9065 
Product name ACECLIDINE 

- Mashkovsky et al., Prog. Drug. Res. (1969). 13:294-339
- Wienstein et al., Molec. Pharmacol. (1975). 11(5):671-689
- Mashkovsky et al., Khim. Pharm. Zh. (1967) (Russian). (3):3
- Barlow et al., Molec. Pharmacol. (1975). 11(5):690-693
 Links
Product code L9065 
Product name ACECLIDINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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