L6033 - IMPERIALINE (3-beta-Chloro-)
IMPERIALINE (3-beta-Chloro-) | Product ID | L6033 |
| Name | IMPERIALINE (3-beta-Chloro-) |
| Molecular formula | C27H42CINO2 |
| Description |
It is a potent medium-lasting selective M2 muscarinic receptor antagonist. Cervane alkaloid , derivative of Imperialine from the plant Petilium eduardi. |
| Biological activity | 3-beta-Chloro-Imperialine, a medium-lasting cholinoblocker of M2 receptors, blocks M2 receptors in the heart at 10 μg/kg (i.v.). 3-beta-Chloro-Imperialine's activity is 10 times higher than that of Imperialine. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
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| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6033 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6033 | Molecular weight | 447 g/mol |
| Product name | IMPERIALINE (3-beta-Chloro-) | Physical form | |
| CAS No. | 153720-49-1 | Melting point | 203-208 °C |
| RTECS | Solubility | In chloroform Not well in acetone, methanol, ethanol, water |
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| Purity | 97% | ||
| Toxicity(LD50) | IVN-MUS LD50: 46 mg/kg | ||
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| Storage & Reconstitution Recommandations |
Store at +4°C, in dark place. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L6033 |
| Product name | IMPERIALINE (3-beta-Chloro-) |
- Eglen et al., "Characterisation of the interaction of the cervane alkaloid, imperialine, at Muscarinic receptors in vitro." Naunyn-Schmiedeberg’s Arch. Pharmacol. (1992) 346:144-151
- Mirzaev, unbublished results on 3-beta-Bromo-Imperialine
Links
| Product code | L6033 |
| Product name | IMPERIALINE (3-beta-Chloro-) |
| External Links |
PubMed
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Biomedical Citations From PubMed
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Toxicology Citations From PubMed
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