L6099 - IMPERIALINE (3-beta-Bromo-)
IMPERIALINE (3-beta-Bromo-) | Product ID | L6099 |
| Name | IMPERIALINE (3-beta-Bromo-) |
| Molecular formula | C27H42NO2Br |
| Description |
It is a M2 muscarinic receptor antagonist and a myorelaxant. It allows the production of 3-alpha-[125I]Iodo-Imperialine by substitution of bromine by [125I] iodine. Steroid alkaloid , derivative of Imperialine from the plant Petilium eduardi, and P. raddeanae. |
| Biological activity | It possesses M2 selective activity: ED50 on cats under anaesthesia (i.v.) 0.015 mg/kg : 65 % of Atropine activity on heart, 1.7 % on isolated ileum, 0.16 % on salivary gland. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 1 x 1mg | 350.00 | ||
| 5 x 1mg | 1 400.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6099 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6099 | Molecular weight | 492.53 g/mol |
| Product name | IMPERIALINE (3-beta-Bromo-) | Physical form | |
| CAS No. | 176039-27-3 | Melting point | 199-202 °C |
| RTECS | Solubility | In chloroform Slightly in methanol and ethanol Not well in acetone |
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| UNIPROT | Optical Activity | ||
| PubChem SID | |||
| PubChem CID | 1648 | ||
| Purity | 98 % (TLC) | ||
| Toxicity(LD50) | IVN-MUS LD50: 48 mg/kg | ||
| Chemical Name | Cevan-6-one,3-bromo-20-hydroxy-, (3b,5a,17b)- (9CI) | ||
| Storage & Reconstitution Recommandations |
Store at +4°C, in dark place. |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L6099 |
| Product name | IMPERIALINE (3-beta-Bromo-) |
- Eglen et al., "Characterisation of the interaction of the cervane alkaloid, imperialine, at Muscarinic receptors in vitro." Naunyn-Schmiedeberg’s Arch. Pharmacol. (1992) 346:144-152
- Mirzaev, unpublished results on 3-beta-Bromo-Imperialine
Links
| Product code | L6099 |
| Product name | IMPERIALINE (3-beta-Bromo-) |
| External Links |
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