In crustaceans, α-latrocrustotoxin-Lt1a binds to neurexin-1-alpha (NRXN1), adhesion G protein-coupled receptor L1 (ADGRL1, also known as latrophilin-1), and receptor-type tyrosine-protein phosphatase S (PTPRS), and induces neurotransmitter exocytosis through two calcium-dependent mechanisms (membrane pore formation and signaling via latrophilin) and a yet to be defined calcium-independent mechanism binds with high affinity to presynaptic membranes; stimulates neurotransmitter release from nerve endings; increases intracellular Ca2+ concentration; the biological activity on nerve endings occurs at 10-10-10-9 M.

Can be stored at 4 °C in presence of sodium azide up to 0.5 mg/ml during one month without any loss of activity or protein aggregation; a small amount of the lyophilized product cannot be dissolved; repeating thawings and freezings causes a partial loss o