L8404-100UG - AGATOXIN IVA (omega-)
(Syn. : omega-AGTX 4A)
Product ID |
L8404-100UG |
Name |
AGATOXIN IVA (omega-) |
Molecular formula |
C217H368N68O60S10 |
Description |
A 48 amino-acids peptide with 4 disulfide bridges
, synthetic, originally isolated from Agelenopsis aperta spider venom.
|
Biological activity |
ω-AGTX-4A is a highly specific P-type Ca2+ channel blocker. High-threshold P-Type Ca2+ current blocking saturation in rat Purkinje neurons occurs with 60-200 nM of the molecule. |
| Safety Data Sheet Available on request, please Contact us Ref. SDS_L8404-100UG : unit price : free of charge |
Product code |
L8404-100UG |
Molecular weight |
5206.5 Da |
Product name |
AGATOXIN IVA (omega-) |
Physical form |
White lyophilized solid |
CAS No. |
145017-83-0 |
Melting point |
|
RTECS |
|
Solubility |
water and saline buffer |
UNIPROT |
P30288 |
Optical Activity |
|
PubChem SID |
|
|
|
PubChem CID |
90488780 |
|
|
Purity |
> 98 % |
|
|
Toxicity(LD50) |
No Data |
|
|
Chemical Name |
|
|
|
Storage & Reconstitution Recommandations |
Stable in freeze-dried state. In solution, keep at -20°C.
|
|
Savety Recommandations |
|
|
Product code |
L8404-100UG |
Product name |
AGATOXIN IVA (omega-) |
- Mintz et al., P-type calcium channels blocked by the spider toxin omega-Aga-IVA. Nature 355:827-828 (1992).