L8130-500UG - SARAFOTOXIN C
(Syn. : SRTX-C, S6C)
| Product ID |
L8130-500UG |
| Name |
SARAFOTOXIN C |
| Molecular formula |
C103H147N27O37S5 |
| Description |
A 21 amino-acids peptide with 2 disulfide bridges
, synthetic, initially isolated from the venom of the Israeli mole viper Atractaspis engaddensis.
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| Biological activity |
Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively). |
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L8130-500UG : unit price : free of charge |
| Product code |
L8130-500UG |
Molecular weight |
2516 Da |
| Product name |
SARAFOTOXIN C |
Physical form |
White lyophilized solid |
| CAS No. |
121695-87-2 |
Melting point |
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| RTECS |
NA |
Solubility |
water and saline buffer |
| UNIPROT |
P13208 |
Optical Activity |
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| PubChem SID |
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| PubChem CID |
16132421 |
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| Purity |
> 98 % |
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| Toxicity(LD50) |
No Data |
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| Chemical Name |
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Storage & Reconstitution Recommandations |
Stable at room temperature, store preferably at 4°C
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| Savety Recommandations |
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| Product code |
L8130-500UG |
| Product name |
SARAFOTOXIN C |
- 1. Matsuo et al (1997) Effects of sarafotoxin S6c on antidiuresis and norepinephrine overflow induced by stimulation of renal nerves in anesthetized dogs. J.Pharmacol.Exp.Ther. ;
2. Miasiro et al (1998) Distinct endothelin-B receptors mediate the effects of sarafotoxin S6c and IRL 1620 in the ileum. J.Cardiovasc.Pharmacol. ;
3. Williams et al (1991) Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes. Biochem.Biophys.Res.Commun. ;
4. Williams et al (1993) Characterization of cloned human endothelin receptors. Life Sci.