L8128-500UG - SARAFOTOXIN A
(Syn. : SRTX-A, S6A)
Product ID |
L8128-500UG |
Name |
SARAFOTOXIN A |
Molecular formula |
C105H156N28O34S5 |
Description |
A 21 amino-acids peptide with 2 disulfide bridges
, synthetic, initially isolated from the venom of the Israeli mole viper Atractaspis engaddensis.
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Biological activity |
Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo. |
| Safety Data Sheet Available on request, please Contact us Ref. SDS_L8128-500UG : unit price : free of charge |
Product code |
L8128-500UG |
Molecular weight |
2514.85 Da |
Product name |
SARAFOTOXIN A |
Physical form |
White lyophilized solid |
CAS No. |
126738-34-9 |
Melting point |
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RTECS |
NA |
Solubility |
water and saline buffer |
UNIPROT |
P13208 |
Optical Activity |
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PubChem SID |
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PubChem CID |
71308664 |
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Purity |
> 98 % |
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Toxicity(LD50) |
No Data |
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Chemical Name |
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Storage & Reconstitution Recommandations |
Stable at room temperature, store preferably at 4°C
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Savety Recommandations |
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Product code |
L8128-500UG |
Product name |
SARAFOTOXIN A |
- 1. Minkes et al (1992) Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic vascular beds. Am.J.Physiol. ;
2. Raffa et al (1996) Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. J.Pharmacol.Exp.Ther. ;
3. Schoeffter and Randriantsoa (1993) Differences between endothelial receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur.J.Pharmacol.