L6285 - COLCHAMINE
(Syn. : Demecolcine)
(Syn. : Demecolcine)
COLCHAMINE | Product ID | L6285 |
| Name | COLCHAMINE |
| Molecular formula | C21H25NO5 |
| Description |
Antineoplastic alkaloid isolated from Colchicum autumnale (Liliaceae Fam.) |
| Biological activity | An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. It stimulates the intrinsic GTPase activity of tubulin, induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal. |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 104.00 | ||
| 100 mg | 416.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6285 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6285 | Molecular weight | 371.43 g/mol |
| Product name | COLCHAMINE | Physical form | Powder |
| CAS No. | 477-30-5 | Melting point | 73-75 °C |
| RTECS | GH0800000 | Solubility | |
| UNIPROT | Optical Activity | [alpha]D -127° (chloroform) | |
| PubChem SID | |||
| PubChem CID | 220401 | ||
| Purity | |||
| Toxicity(LD50) | |||
| Chemical Name | 6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-benzo(alpha)heptalen-9(5H)-one | ||
| Storage & Reconstitution Recommandations |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L6285 |
| Product name | COLCHAMINE |
- Kh. N. Aripov, "The chemistry of plant substances in Uzbekistan", Chemistry of Natural Compounds (1995), Volume 31, Issue 1, pp 2-15
Links
| Product code | L6285 |
| Product name | COLCHAMINE |
| External Links |
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