VINCANIDINE HCl
Product ID L6282 
Name VINCANIDINE HCl 
Molecular formula C19H20O2N2, HCl
Description

It is a dopamine receptor stimulating agent.


Indolinine alkaloid , extracted from roots of Vinca erecta (Apocynaceae fam.)
Biological activity

It acts like a Dopaminic receptors ligand as an emetic compound with central mechanism of action.

Field of Use:

Theoretically it can be used, as representative of original chemical class of indolinine alkaloids with dopaminic positive activity. Considering its structural similarity with Strychnine effects on glycine receptors are not excluded. Known partial analogs are apomorphine and licorine.

Recommended doses: from 1.0 to 10.0 mg/kg (i.v.), depending on experiment targets

Recommended concentrations: between 3.10<sup>-6</sup> and 10<sup>-5</sup> g/m

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 104.00

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100 mg 416.00

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 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6282 : unit price : free of charge
 Chemical and Physical Properties
Product code L6282  Molecular weight 344.5 g/mol
Product name VINCANIDINE HCl  Physical form Light brown powder
CAS No. Melting point 185-186 °C
RTECS Solubility In water up to 2-3% concentration
Easily in ethanol
UNIPROT Optical Activity [α] -175° (methanol)
PubChem SID    
PubChem CID 101627612    
Purity ≥ 97%. Method for purity assay: mass spectrometry    
Toxicity(LD50) mice (s.c.): 85 mg/kg    
Chemical Name 12-hydroxynorfluorocurarine hydrochloride    
Storage & Reconstitution
Recommandations

Store in dry, cool and dark place


in water, up to 2%
 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6282 
Product name VINCANIDINE HCl 

- Kh. U. Ubaev, P. Kh. Yuldashchev, S. Yu. Yunusov, "Structure of vincanidine, an alkaloid from the roots of vinca erecta", Bulletin of the Academy of Sciences of the USSR, Division of chemical science (November 1965), Volume 14, Issue 11, pp 1958-1960
- Sultanov M.B. et al., Izvestia Ac.Sci.Uz.SSR, (Ser.med.),1959, No 1, p.29 – 37
- Kurmukov A.G. et al., in book: “Pharmacology of alkaloids and cardiac glycosides”,Tashkent, 1971, p. 27 – 30
 Links
Product code L6282 
Product name VINCANIDINE HCl 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
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