L6280 - TRACHELANTHAMINE
TRACHELANTHAMINE | Product ID | L6280 |
| Name | TRACHELANTHAMINE |
| Molecular formula | C15H27NO4. |
| Description |
It is known as a weak hypotensive with moderate M- and N-cholinolytic activities. It is possibly cytotoxic Pyrrolizidine alkaloid, extracted from the plant Trachelanthus korolkowia, (Boraginaceae Fam.) |
| Biological activity | Moderate M- and N-cholinolytic properties of the Trachelanthamine are described. In view of its structural similarity with Heliotrin, weak cyto- and hepato-toxic activities are expected. Trachelantamine can be used in structure-activity studies on pyrrolizidine alkaloid cyto- and hepato-toxic compounds. Recommended doses: In vivo experiments: 1.0 - 10.0 mg/kg In vitro: 10-6 - 10-5 g/ml |
Packaging and Prices
| Packaging | Price (€) | Quantité | Buy Now |
|---|---|---|---|
| 20 mg | 104.00 | ||
| 100 mg | 416.00 | ||
| For quotation of big quantities, please Contact us | |||
Product Technical Documents
 | Safety Data Sheet Available on request, please Contact us Ref. SDS_L6280 : unit price : free of charge |
Chemical and Physical Properties
| Product code | L6280 | Molecular weight | 285.38 g/mol |
| Product name | TRACHELANTHAMINE | Physical form | White crystalline powder |
| CAS No. | 302-27-2 | Melting point | 91-92 °C |
| RTECS | AR5960000 | Solubility | In water |
| UNIPROT | Optical Activity | Non active | |
| PubChem SID | |||
| PubChem CID | 245005 | ||
| Purity | > 97% | ||
| Toxicity(LD50) | IVN-MUS LD50: 139 mg/kg SCU-MUS: 1950 mg/kg |
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| Chemical Name | [(1R,8S)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-yl]methyl (2R)-2-hydroxy-2-(1-hydroxyethyl)-3-methyl-butanoate | ||
| Storage & Reconstitution Recommandations |
Keep in dark and dry place. compound is soluble in water |
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| Savety Recommandations | For research use only — not intended for food, diagnostic or therapeutic use |
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Bibliographic References
| Product code | L6280 |
| Product name | TRACHELANTHAMINE |
- Menshikov G.P.e.a.J.Organic Chemistry,1941,v.11,p.209 (Rus.).
- Mashkovsky M.D.//Pharmacol. And Toxicol.,1941,No2, pp 19-27 (Rus.).
- Mc.Kenzie//Austral J.Exp.Biol.and Med.Sci.,1958,v.36,No 1.pp.11-21(Eng.).
- Sadritdinov S.F.e.a.//Pharmacology of plants alkaloids and its application in medicine.,1980,Tashkent,p.80. (Rus)
Links
| Product code | L6280 |
| Product name | TRACHELANTHAMINE |
| External Links |
PubMed
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Toxicology Citations From PubMed
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