LYCOCTONINE
Product ID L6263 
Name LYCOCTONINE 
Molecular formula C25HNO7
Description

This alkaloid is obtained from Aconitum lycoctonum and also from other species of Aconitum and Delphinium.


Diterpene Alkaloid. The base alkaloid methyllicaconotine is isolated from Delfinium rotundifolium Afan. Plant (Ranunculaceae fam.)
Biological activity

It is a ganglion blocking agent, curare-like compound. It belongs to an original chemical class of reversible nicotinic receptors blocker

 Packaging and Prices

Packaging Price (€) Quantité Buy Now
20 mg 104.00

add to cart add to cart

100 mg 416.00

add to cart add to cart

For quotation of big quantities, please Contact us
 Product Technical Documents
Safety Data Sheet Available on request, please Contact us
Ref. SDS_L6263 : unit price : free of charge
 Chemical and Physical Properties
Product code L6263  Molecular weight 467.59 g/mol
Product name LYCOCTONINE  Physical form White with yellow shade crystalline powder
CAS No. 26000-17-9 Melting point 126-131 °C
RTECS AR5541200 Solubility Easily soluble in chloroform,
Moderately in methanol,
Poorly soluble in acetone and ethanol
UNIPROT Optical Activity [alpha]D20 +52° (ethanol)
PubChem SID    
PubChem CID 57506221    
Purity >95%. Method of determination of purity: by melting point, TLC [on aluminii oxide in the system benzen-ethanol (20:1), on silicagel in system chloroform-methanol (4:1)], IR-, PMR-spectora - 0,42, on silicagel, KSK, mass - spectrometry    
Toxicity(LD50) IVN-MUS LD50: 170 mg/kg    
Chemical Name 1alpha‚6beta‚14alpha‚16beta-Tetramethoxy‚ 7beta‚8beta-dihydroxy‚4beta-hydroxymethylen‚ N-ethylaconitan    
Storage & Reconstitution
Recommandations
 
Savety Recommandations

For research use only — not intended for food, diagnostic or therapeutic use

 
 Bibliographic References
Product code L6263 
Product name LYCOCTONINE 

- Salimov, B. T.; Tashkhodzhaev, B.; Dzhakhangirov, F. N., "Structure and biologicalactivity of demethyleneldelidine and its dihydro-?-lactone", Chemistry of Natural Compounds (2009) 45: 685-689 , November 24, 2009
- Salimov, B. T., "Alkaloids of Delphinium corymbosum", Chemistry of Natural Compounds (2004) 40: 579-581 , November 01, 2004
- Boronova, Z. S.; Sultankhodzhaev, M. N., "Alkaloids of Delphinium poltoratskii", Chemistry of Natural Compounds (2000) 36: 390-392 , July 01, 2000
- Dzhakhangirov, F. N.; Kasymova, K. R.; Sultankhodzhaev, M. N.; Salimov, B. T.; Usmanova, S. K.; Shakirov, R. Sh, "Toxicity and local anesthetic activity of diterpenoid alkaloids", Chemistry of Natural Compounds (2007) 43: 581-589 , September 01, 2007
- Pelletier S., Mody N., Joshi S., Schramm L. In: Alkaloids: Chemical and biological perspectives. Ed. Pelletier S., Willey J. New-York, 1984, v.2, p. 418
- Dzhachangirov F., Salimov B., Bessoinova I., Sultankhodzhaev M. Search and study of curare-like drugs among diterpene alkaloids. Chim. Prirod. Soedin., 1995, No 6. p. (Rus.)
 Links
Product code L6263 
Product name LYCOCTONINE 
External Links PubMed
Biomedical Citations From PubMed
Toxicology Citations From PubMed
PubChem CID
click to zoom

LOGIN
Welcome, click here to   Login !




Adress:
ZA Les Auréats, 845 Avenue Pierre Brossolette
26800 PORTES lès VALENCE - FRANCE

Phone:
+33 475 419 191

Email:
latoxan[@]latoxan.com

Web link:
www.latoxan.com